How painful is microneedling - really? Whether you are sitting in a waiting room about to have tiny needles pressed into your face for the first time, or you are at home staring at your red, stinging reflection wondering if something went wrong, this is the question that brought you here. And it is a completely valid one. Pain anxiety is the single biggest barrier to booking a microneedling appointment, and it is also the number one source of post-procedure panic when your skin looks and feels like it has been through something intense. This guide covers everything you need to know about post-treatment care and microneedling aftercare - from what the session actually feels like, to what your skin will do hour by hour in the days that follow, to how you can speed up recovery with the right approach.
Here is the honest framing before we go any further. The science referenced throughout this article comes from peer-reviewed microneedle research published in journals like the Journal of Cosmetic Dermatology, Advanced Healthcare Materials, and Biosensors and Bioelectronics. These studies focus on microneedle patch technology for wound care, drug delivery, and radiofrequency microneedling for specific skin conditions. Where cosmetic-specific facial microneedling pain data is limited in these sources, this article will tell you directly rather than fill the gap with guesswork. You deserve transparency, not inflated claims.
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What Is Microneedling and Why Does It Involve Pain at All?
Before we talk about how much it hurts, it helps to understand why it hurts at all. Microneedling works by creating thousands of tiny, controlled micro-injuries in your skin using fine needles. These punctures are not random damage - they are a deliberate trigger. Your skin responds by ramping up its natural repair processes, producing new collagen, improving texture and tone, and creating temporary microchannels that allow serums and active ingredients to absorb far more effectively than they would on intact skin.
Different microneedling formats exist, and each one interacts with your skin - and your nerve endings - differently. Professional pen devices use adjustable needle depths and stamp vertically into the skin. RF (radiofrequency) microneedling adds energy through the needles, combining mechanical puncture with controlled heat. Dermarollers use shorter, fixed-length needles that roll across the surface. And then there are dissolvable microneedle patches, which are engineered primarily for clinical wound care and drug delivery, often designed to dissolve into the skin while releasing therapeutic compounds.
The reason microneedling can hurt is straightforward. The needles penetrate your outer skin barrier - the epidermis - and reach deeper layers where nerve endings live. The depth of the needles, the speed of the device, the specific area of your face being treated, and whether or not you have been numbed all influence how much sensation you feel. Importantly, some microneedle systems have been specifically engineered to include pain relief as part of their design. Research by Nibir et al. (2026) describes dissolvable microneedle patches that co-deliver lidocaine alongside therapeutic agents for diabetic wound treatment, and Shao et al. (2026) developed spatial-efficacy microneedles designed for simultaneous analgesia and healing acceleration. The fact that pain mitigation is built directly into the technology tells us that discomfort is a recognized engineering challenge in microneedle science - not a surprise side effect you should feel embarrassed about.
Here is a quick comparison of the main formats and what the research covers:
| Format | Setting | Needle Depth | Pain Relevance | Covered in Sources? |
|---|---|---|---|---|
| Professional pen device | Clinical | Adjustable, deeper | Higher sensation, numbing typically used | Not directly |
| RF microneedling | Clinical | Moderate + energy | Adds heat sensation | Yes - Safir et al. 2026 |
| Dermaroller | Home or clinical | Shorter, fixed | Variable | Not directly |
| Dissolvable microneedle patch | Research/clinical | Very short | Engineered for minimal pain, can include lidocaine | Yes - Nibir et al. 2026, Shao et al. 2026 |
The studies cited in this article focus on microneedle patches for wound care and drug delivery (Nibir et al. 2026; Saurabh et al. 2026; Pereira et al. 2026), microneedle-integrated biosensors for wound monitoring (Pereira et al. 2026), and RF microneedling for hidradenitis suppurativa (Safir et al. 2026). Cosmetic facial microneedling pain scores are not quantified in these sources. Where that gap exists, the article flags it clearly.
Does Microneedling Hurt?
This is the question that gets typed into search engines more than almost any other microneedling query, and the honest answer is - yes, to some degree, it does. But the intensity of that sensation depends on several factors that are largely within your control or your provider's control. With proper numbing, most people describe the experience as tolerable pressure with intermittent prickling rather than outright pain. Without numbing, the sensation is significantly more intense, which is precisely why analgesia-focused microneedle designs exist in the research literature. Shao et al. (2026) specifically engineered microneedle systems for "simultaneous analgesia and healing acceleration," confirming that the scientific community treats pain management as a core component of microneedle treatment - not an afterthought.
The sensation most commonly described includes prickling, vibrating pressure, a scratching feeling, and warmth in certain areas. Some people tear up when the device passes near the nose or under the eyes - not because the pain is unbearable, but because those areas have dense nerve endings and the body reflexively responds. The important thing to understand is that there is a range of normal, and feeling something does not mean something is wrong.
Does Face Microneedling Hurt?
The face is the most common treatment area, and it is also one of the most sensitive. Sensation varies meaningfully by zone. The cheeks are generally the most tolerable area - there is more tissue cushion and slightly less nerve density. The forehead and temples tend to be more sensitive because the skin is thinner and closer to bone. The area around the nose and upper lip is almost universally described as the most uncomfortable part of a facial microneedling session, with patients often reporting a sharp, stinging quality that is noticeably different from the rest of the face.
Here is a helpful framework for distinguishing expected sensations from warning signs during a facial session:
✅ Expected sensations - prickling, mild stinging, warmth, tearing up near the nose and eye area, wanting to grip the chair during sensitive spots, a vibrating or scratching feeling across the cheeks and forehead.
🚩 Not expected - sharp shooting pain that does not resolve between passes, a burning sensation that persists and intensifies rather than fading, feeling like the skin is being torn or scraped raw. If you experience any of these, tell your provider immediately so they can adjust depth, speed, or numbing.
It is worth noting that specific cosmetic facial pain scores are not quantified in the studies referenced here. The principle that microneedle procedures involve meaningful sensation - and that analgesia is a design priority - is well-supported by the wound-care microneedle literature (Nibir et al. 2026; Shao et al. 2026).
Do They Numb You For Microneedling?
In the vast majority of professional clinical settings, yes. Topical anesthetic - most commonly a lidocaine-based numbing cream - is applied to the treatment area before the session begins. This is standard practice, not an optional upgrade, and most reputable providers include it as part of the procedure. The concept of integrated analgesia is validated extensively in microneedle research. Nibir et al. (2026) developed dissolvable microneedle patches that co-deliver lidocaine alongside levofloxacin for diabetic wound treatment, and Shao et al. (2026) designed spatial-efficacy microneedles that provide simultaneous pain relief and healing acceleration. These innovations confirm that local anesthesia is treated as a core consideration in microneedle system design, not a luxury.
Do They Numb Your Face Before Microneedling?
Yes, and the timing matters more than most people realize. Topical numbing cream is typically applied 20 to 45 minutes before the actual microneedling begins. If the cream does not sit long enough, it will not penetrate deeply enough to block sensation effectively, and you will feel significantly more during the procedure. This is one of the most common reasons patients report that "microneedling really hurt" - not because the treatment was too aggressive, but because the numbing was rushed.
Before your appointment, ask your provider three things. First, is topical numbing included in the procedure? Second, how long will the numbing cream be left on before treatment starts? Third, should you arrive with a clean, product-free face to maximize the numbing cream's absorption? These simple questions can meaningfully change your comfort during the session.
The specific protocols for cosmetic numbing cream application are not detailed in the provided studies, which focus on lidocaine delivery through microneedle patches rather than topical cream application (Nibir et al. 2026). However, the underlying principle - that effective local anesthesia is essential for patient comfort during microneedle procedures - is strongly supported.
How Painful Is Microneedling On Face?
On a practical level, most patients with adequate numbing rate facial microneedling somewhere in the range of mild to moderate discomfort - not painless, but not the kind of pain that makes you regret the decision. The sensation is often compared to having a slightly aggressive cat lick your face, or running sandpaper lightly across sunburned skin. It is not sharp in the way a needle injection is sharp. It is more of a widespread, buzzing, prickling sensation that intensifies in certain zones and eases in others.
The variables that shift the experience from "barely felt it" to "that was rough" include needle depth (deeper settings for scarring or advanced collagen induction hurt more than shallow settings for general rejuvenation), number of passes over each area, the specific device used, your individual pain tolerance, and - most critically - the quality and duration of your numbing preparation.
How Painful Should Microneedling Be?
There is a difference between "this is uncomfortable but manageable" and "this feels wrong." Microneedling should feel like controlled, tolerable sensation - not agony. If you are gritting your teeth through every pass, something needs to be adjusted. Good providers check in throughout the session and will modify needle depth, device speed, or add additional numbing if you are struggling. The goal of microneedling is a controlled injury response, and that response does not require you to be in significant pain to be effective.
The wound-care microneedle literature reinforces this principle. Researchers designing microneedle systems for clinical use consistently prioritize minimizing patient discomfort while maintaining therapeutic effectiveness (Nibir et al. 2026; Shao et al. 2026). The same logic applies to cosmetic microneedling - discomfort should be managed, not endured as proof the treatment is "working."
How Painful Is RF Microneedling?
RF microneedling adds a layer of radiofrequency energy delivered through the needles into the skin, which means you are experiencing both mechanical puncture and controlled heat simultaneously. This combination plausibly increases sensation compared to mechanical-only microneedling. Safir et al. (2026) published a real-world retrospective study on fractional microneedling radiofrequency for hidradenitis suppurativa, demonstrating clinical efficacy and safety across diverse anatomical sites. While their study focused on a specific inflammatory skin condition rather than cosmetic facial treatment, it confirms that RF microneedling is used clinically with established safety protocols.
Most RF microneedling protocols account for the added sensation by using stronger topical numbing, and some providers offer additional comfort measures. The heat component is often described as a deep warmth or a brief flash of heat with each pulse, layered on top of the prickling from the needles themselves. If you have had standard microneedling before, expect RF to feel noticeably more intense.
How Painful Is Microneedling With Numbing Cream?
With properly applied numbing cream, microneedling is genuinely manageable for most people. Topical lidocaine is the most common numbing agent, and microneedle patch research confirms that lidocaine can be delivered effectively through skin to achieve local analgesia (Nibir et al. 2026). However, numbing cream does not eliminate all sensation. Most patients still feel pressure, vibration, and mild prickling, especially in sensitive zones like the upper lip, nose, and temples.
The key factors that determine how well your numbing cream works are concentration (prescription-strength is more effective than over-the-counter), application thickness (a generous layer performs better than a thin one), duration (the full recommended wait time matters - do not rush it), and occlusion (some providers cover the cream with plastic wrap to enhance absorption). If your provider's numbing protocol feels inadequate, speak up before the treatment begins rather than trying to push through.
How Painful Is Microneedling With PRP?
PRP - platelet-rich plasma - involves a blood draw before the microneedling session, which adds a standard needle stick to the overall experience. This can increase procedural anxiety, especially for patients who are already nervous about the microneedling itself. However, the PRP is applied topically to the skin during or after the microneedling treatment. It should not increase the pain of the needling itself.
Some patients report that PRP application on freshly microneedled skin creates a mild stinging or warming sensation, though this is generally brief. PRP microneedling pain is not addressed in the provided studies, and this section reflects general procedural knowledge. Discuss any concerns about PRP-specific discomfort with your provider before your appointment (Pereira et al. 2026 - general microneedle context only).
How Painful Is Microneedling Without Numbing?
Significantly more intense. Without topical anesthetic, you feel every needle penetration without the buffer that lidocaine provides, and the cumulative sensation over a full facial treatment can be overwhelming for many patients. This is not a matter of toughness - it is physiology. Your facial skin has a high density of sensory nerve endings, and hundreds of needle punctures per second will register.
The existence of analgesia-integrated microneedle systems speaks directly to this point. Researchers have invested significant effort into co-delivering lidocaine with microneedle treatments (Nibir et al. 2026) and designing systems for simultaneous analgesia and healing (Shao et al. 2026) precisely because pain mitigation is treated as technically necessary, not optional, in microneedle engineering. If your provider does not offer numbing, ask why. If you are using an at-home device without prescription numbing, expect more sensation and use the shortest appropriate needle length.
Does Microneedling At Home Hurt?
At-home microneedling devices typically use shorter needle lengths than professional devices, which means less penetration depth and generally less sensation. However, "less" does not mean "none." You will still feel prickling and pressure, and without professional-grade numbing cream, even short needles can be uncomfortable, particularly on sensitive facial areas.
At-home devices are not covered in the provided research, which focuses on clinical-grade and engineered microneedle systems designed for controlled, sterile application environments (Pereira et al. 2026; Nibir et al. 2026). The wound-care literature emphasizes sterile, controlled application for a reason - improper at-home use carries infection and scarring risk. If you choose to microneedle at home, understand that you are trading the precision, safety, and comfort management of a clinical setting for convenience.
Does Microneedling Roller Hurt?
Dermarollers use a rolling motion across the skin rather than the vertical stamping action of pen devices. This means the needles enter the skin at an angle, which some users find creates a slightly different - and sometimes less comfortable - sensation than vertical penetration. The rolling action can also create more surface-level tearing if used with too much pressure or on overly sensitive skin.
Shorter, fixed-length needles on dermarollers generally mean less overall depth penetration, but the sensation is less controlled because you are manually determining pressure and speed. Pain with a dermaroller depends heavily on needle length, your technique, and whether you are using any topical numbing.
How Painful Is A Derma Roller?
For most people using a dermaroller with needle lengths under 0.5mm, the sensation is best described as mild to moderate prickling - noticeable but not distressing. As needle length increases toward 1.0mm or beyond, discomfort increases meaningfully, and these longer lengths are generally not recommended for unsupervised home use. The general microneedle research context (Pereira et al. 2026) reinforces that needle penetration depth directly correlates with both therapeutic effect and sensation intensity - shorter needles are gentler but may deliver less clinical benefit.
Does Professional Microneedling Hurt?
Professional microneedling is performed in a controlled environment with adjustable needle depth, sterile technique, effective numbing, and a trained operator who can adjust settings based on your real-time feedback. This means that while the treatment may be more intense than at-home devices (because deeper depths are typically used for clinical results), the pain management is also substantially better.
The clinical use of RF microneedling across diverse anatomical sites with reported safety and efficacy (Safir et al. 2026) and the sophisticated engineering of wound-care microneedle patches with integrated analgesia (Nibir et al. 2026; Shao et al. 2026) both reflect the level of precision and safety engineering that characterizes professional-grade microneedle systems. A skilled provider using appropriate numbing and communicating with you throughout the session can make a significant difference in your comfort level.
Does Microneedling Also Hurt Afterwards?
Yes - but the nature of the sensation shifts. During the treatment, you feel the needles actively penetrating your skin. Afterwards, the sensation transitions to something more like a sunburn. Your skin will feel warm, tight, and sensitive to touch. This post-procedure discomfort is generally most intense in the first few hours and gradually fades over the following one to three days.
The concept of post-treatment discomfort is acknowledged in the microneedle research through the design of systems that address both pain and healing simultaneously. Shao et al. (2026) developed microneedles with "amplified immunomodulation" that accelerate wound healing while providing analgesia, recognizing that the recovery phase itself involves discomfort that benefits from active management.
How Long Will My Face Hurt After Microneedling?
Most patients report that the acute sunburn-like sensation fades within 12 to 24 hours. Residual tightness, sensitivity, and mild tenderness can persist for two to four days depending on the aggressiveness of the treatment and your skin's individual healing response. RF microneedling recovery may take slightly longer due to the added thermal component.
Here is a general day-by-day orientation for what to expect. These timeframes reflect general clinical guidance and are not derived from the provided studies, which focus on wound-care microneedle patches and RF microneedling for hidradenitis suppurativa. Treat this as orientation and defer to your provider's specific instructions.
➡️ Day 0 (treatment day) - Skin is red, warm, potentially swollen. Feels like a moderate sunburn. Microchannels are open, making skin highly absorptive. Apply only provider-approved serums or recovery products with gentle, clean hands. Do not touch your face unnecessarily, apply makeup, use active ingredients like retinol, vitamin C, or AHAs/BHAs, or expose your skin to direct sun.
➡️ Day 1 - Redness may peak or begin fading. Tightness and dryness are common. Mild itching may start, which is actually a sign of healing. Use a gentle cleanser, a hydrating recovery serum, and SPF if going outside. Avoid exfoliation and hot water on your face.
➡️ Days 2 to 3 - Redness continues to fade for most people. Skin may feel rough or slightly flaky as the surface layer turns over. Dryness can intensify. Continue gentle hydration and sun protection. Avoid picking or peeling any flaking skin.
➡️ Days 4 to 5 - Most visible redness and swelling have resolved. Skin texture may still feel slightly rough. You can typically begin reintroducing your normal skincare products, but check with your provider about timing for active ingredients.
➡️ Days 6 to 7 - Skin should feel largely normal. Some patients notice their skin starting to look better than before treatment as the initial collagen remodeling begins. Full results develop over weeks to months as deeper collagen remodeling continues.
How Does Skin Feel After Microneedling?
In the immediate aftermath, your skin feels hot, tight, and sensitive - very similar to a moderate sunburn. You may notice mild swelling, particularly around the eyes and cheeks. Pinpoint bleeding during the session is normal with deeper needle depths and typically stops within minutes to hours.
Here is a reference table for common post-treatment symptoms:
| Symptom | Expected Duration | When to Contact Your Provider |
|---|---|---|
| Redness | Hours to 2-3 days | If intensifying after day 2-3 or accompanied by heat and tenderness |
| Swelling | 1-2 days | If increasing after day 2 or painful to touch |
| Tightness and dryness | 2-5 days | If cracking, severe peeling, or skin feels raw |
| Warmth and stinging | Several hours | If burning persists beyond 24 hours |
| Pinpoint bleeding | Stops within minutes to hours | If bleeding resumes or oozing develops later |
The design priorities in microneedle research reflect the importance of post-treatment comfort and healing. Shao et al. (2026) specifically engineered microneedles for healing acceleration alongside pain relief, and Pereira et al. (2026) developed microneedle-integrated biosensors for smart wound monitoring - both acknowledging that the post-procedure period requires active attention and management, not just waiting it out.
How To Make Microneedling Less Painful?
Pain management during microneedling is not about being tough. It is about being smart. Here are practical strategies to reduce discomfort before, during, and after your session.
➡️ Before the session - Ensure your provider uses adequate numbing cream with sufficient application time. Arrive with a clean, product-free face to maximize numbing cream absorption. Avoid caffeine and alcohol the day of treatment, as both can increase skin sensitivity. If you have significant anxiety, discuss this with your provider beforehand - some offices offer calming techniques or adjust their approach for anxious patients.
➡️ During the session - Communicate with your provider throughout. If a particular area is especially painful, say so - they can adjust needle depth, slow down, or apply additional numbing. Deep, steady breathing genuinely helps manage sensation. Listening to music or a podcast through earbuds can serve as a useful distraction.
➡️ After the session - Use only gentle, hydrating, provider-approved recovery products on freshly treated skin. Avoid anything with fragrance, active acids, or retinol for the time period your provider specifies. Keep your skin cool - a clean, cool (not ice-cold) compress can help if the sunburn sensation is intense. Stay out of direct sunlight and apply broad-spectrum SPF religiously once your provider gives the green light.
The principle of integrated pain management is central to modern microneedle design. The co-delivery of therapeutic agents with lidocaine (Nibir et al. 2026) and the development of simultaneous analgesia and healing systems (Shao et al. 2026) both demonstrate that the most advanced microneedle research treats comfort as inseparable from clinical effectiveness.
Microneedling Aftercare and Recovery - What Your Skin Needs to Heal Faster
The hours and days after microneedling are when the real work happens beneath your skin's surface. Collagen remodeling is underway, microchannels are closing, and your skin is in a state of heightened vulnerability and absorption. What you put on your skin during this window matters enormously.
➡️ Products to use - Gentle, fragrance-free cleansers. Hydrating serums with hyaluronic acid. Recovery-focused formulations designed for post-procedure skin. Broad-spectrum SPF 30 or higher once your provider approves sun exposure. If your provider recommends exosome-based recovery products, these can be particularly well-suited for the post-microneedling window when your skin's absorption is enhanced through open microchannels.
➡️ Products to avoid for at least 48 to 72 hours (or as directed by your provider) - Retinol, retinoids, and vitamin A derivatives. AHAs, BHAs, and chemical exfoliants. Vitamin C serums (can sting on compromised skin). Fragranced moisturizers or cleansers. Physical scrubs or exfoliating brushes. Makeup (mineral or traditional) unless explicitly cleared by your provider.
➡️ Behaviors to avoid - Direct sun exposure for at least one week. Hot showers, saunas, and steam rooms for 48 to 72 hours. Intense exercise that causes heavy sweating for 24 to 48 hours. Touching your face with unwashed hands. Picking at any flaking or peeling skin.
Microneedle research consistently emphasizes the wound-healing environment as critical to outcomes. Pereira et al. (2026) developed microneedle-integrated biosensors specifically for monitoring wound environments in real time, reinforcing that what happens to the skin after needling - the healing conditions, the products applied, the environmental exposures - directly influences results.
Skin of Color Considerations for Microneedling
If you have medium to deep skin tones (Fitzpatrick types III through VI), microneedling conversations need to include post-inflammatory hyperpigmentation (PIH) risk. Darker skin tones are more prone to developing temporary darkening at treatment sites as part of the inflammatory healing response. This is not a complication of poor technique - it is a physiological reality of melanin-rich skin that requires proactive management.
Discuss your specific skin type with your provider before treatment. Sun protection after microneedling is critical for all skin types but especially important for skin of color to minimize PIH risk. The RF microneedling safety profile documented by Safir et al. (2026) across diverse anatomical sites offers some reassurance about the broader tolerability of microneedle-based treatments, though their study focused on hidradenitis suppurativa rather than cosmetic facial treatment in skin of color specifically.
When Will You Actually See Results?
Microneedling results do not appear overnight. The controlled injury you experienced triggers a collagen remodeling process that unfolds over weeks to months. Most patients notice initial improvements in skin texture and glow within one to two weeks as the surface heals. Deeper improvements in fine lines, acne scarring, and overall firmness typically become visible at the four to eight week mark and continue developing for up to six months after a treatment series.
This delayed gratification can feel frustrating when you are in the thick of recovery and your skin looks worse before it looks better. But the biological process is working beneath the surface. The wound-healing cascade that microneedle research focuses on (Nibir et al. 2026; Shao et al. 2026; Pereira et al. 2026) confirms that the repair response triggered by controlled micro-injuries involves multiple phases - inflammation, proliferation, and remodeling - that play out over an extended timeline.
Frequently Asked Questions
How painful is microneedling on a scale of 1 to 10?
Most patients with adequate numbing rate it between 2 and 4 out of 10 - uncomfortable but manageable. Without numbing, ratings climb to 5 to 7 depending on treatment depth and facial area. Sensitive zones like the upper lip and nose always rate higher.
Can I wear makeup after microneedling?
Most providers recommend avoiding makeup for at least 24 to 48 hours after treatment. Your microchannels are open and your skin is vulnerable to irritation and potential contamination. Follow your provider's specific timeline before reapplying any cosmetics.
Is microneedling safe for dark skin tones?
Microneedling can be performed on all skin tones, but darker skin types have a higher risk of post-inflammatory hyperpigmentation. Work with an experienced provider who understands Fitzpatrick skin typing, and prioritize strict sun protection during recovery.
How long does redness last after microneedling?
Redness typically lasts from several hours to two or three days for standard microneedling. RF microneedling may cause redness that persists slightly longer. If redness intensifies after day three or is accompanied by increasing heat and tenderness, contact your provider.
Can I go in the sun after microneedling?
Direct sun exposure should be avoided for at least one week after microneedling. Your skin is more vulnerable to UV damage while healing. Once cleared by your provider, apply broad-spectrum SPF 30 or higher diligently, especially for the first several weeks post-treatment.
How many microneedling sessions do I need to see results?
Most providers recommend a series of three to six sessions spaced four to six weeks apart for optimal collagen remodeling. Single sessions can provide a glow-up effect, but structural improvements in scarring and fine lines require cumulative treatment.
Is at-home microneedling as effective as professional treatment?
At-home devices use shorter needles and produce less dramatic results than professional treatments. They also lack the controlled depth, sterile environment, and numbing protocols available in a clinical setting. Professional microneedling delivers deeper penetration and more significant collagen induction.
References
Nibir AR, Akther J, Joy FU, Foyez T, Uddin MB, Sharker SM. Treatment of diabetic wounds using dissolvable microneedle patches co-delivering levofloxacin and lidocaine. Journal of Materials Chemistry B. Published online February 18, 2026. doi:10.1039/d6tb00040a. PMID: 41705355.
Saurabh S, Kumar D, Soni S. PMVE/MA-based microneedle patches for rapid transdermal delivery of vitamin B12: fabrication and evaluation. Drug Delivery and Translational Research. Published online February 18, 2026. doi:10.1007/s13346-026-02055-3. PMID: 41708905.
Pereira RL, Muñoz-Berbel X, Sillankorva S. Microneedle-integrated biosensors for smart wound monitoring. Biosensors and Bioelectronics. 2026;302:118547. doi:10.1016/j.bios.2026.118547. PMID: 41724119.
Safir A, Taleb E, Berzin D, Arieli M, Liassidou A, Shehadeh W, Hafner A, Artzi O. Fractional microneedling radiofrequency for hidradenitis suppurativa: a real-world retrospective study demonstrating clinical efficacy and safety across diverse anatomical sites. Journal of Cosmetic Dermatology. 2026;25(3):e70748. doi:10.1111/jocd.70748. PMID: 41732823.
Shao Z, Wang W, Wang Y, Chen S, Ling Z, Zhou X, Zhao W, Zhao C. Simultaneous analgesia and healing acceleration: spatial-efficacy microneedles with amplified immunomodulation for diabetic wounds. Advanced Healthcare Materials. Published online February 24, 2026:e04760. doi:10.1002/adhm.202504760. PMID: 41735785.
