The 72-Hour+ Cream

50 ml / 1.7 fl oz

✔ Post-procedure recovery cream for the first 72 hours after microneedling, RF microneedling, laser, IPL, and light chemical peels - the window when skin is most reactive

✔ Aloe + Algae Complex: organic aloe vera (the #1 ingredient by concentration) with red algae polysaccharides calms the look of redness and supports a comfortable-feeling barrier

✔ Two molecular weights of hyaluronic acid for immediate and lasting-looking overnight hydration

✔ A fragrance-free post procedure face cream that fits any post procedure skin care routine - layers over our exosome serum at night, under SPF by day

✔ 99% natural origin, 42% organic - COSMOS Organic certified by EcoCert. Zero retinol, acids, or fragrance. Vegan, dermatologically tested. Nightly for the first 72 hours, then as your evening cream through recovery

Price
Regular price
$49.00
Sale price
$49.00
Regular price
30-Day Money-Back Guarantee
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No Synthetic Fragrance
COSMOS Natural Certified

Complete the recovery routine

Exosome Serum for Post-Procedure Skin

Exosome Serum for Post-Procedure Skin

AM + PM - exosome support

$79.00
Ceramide Repair Complex

Ceramide Repair Complex

Night cream from day 4

$49.00
Daily Defense Moisturiser

Daily Defense Moisturiser

Every morning - protect

$39.00
How It Works

The first 72 hours after an aesthetic procedure are when skin looks and feels most reactive - and when most products are too harsh to help. This cream is built for exactly that window: no retinol, no acids, no essential oils, no fragrance.

Organic aloe vera - the #1 ingredient by concentration - calms the look of redness while red algae polysaccharides support a comfortable-feeling barrier. Two molecular weights of hyaluronic acid hydrate at the surface and hold moisture through the night, so skin looks calmer and feels softer by morning.

How to Use

Apply each evening to clean, dry skin. Massage a pearl-sized amount gently across the face and neck and allow to absorb.

Use nightly for the first 72 hours after any aesthetic procedure - once your provider clears topicals - then continue as your daily evening cream for the remainder of recovery. Follow with SPF each morning.

Ingredients

Aqua, Aloe Barbadensis (Aloe) Leaf Juice*, Simmondsia Chinensis (Jojoba) Seed Oil*, Glycerin, Pentylene Glycol, Polyglyceryl-3 Stearate, Cetearyl Alcohol, Coco-Caprylate, Dicaprylyl Carbonate, Isoamyl Laurate, Hydrolyzed Rhodophyceae Extract, Mangifera Indica (Mango) Seed Butter*, Cellulose, Caprylic/Capric Triglyceride, Xanthan Gum, Octyldodecanol, Potassium Hydroxide, Sodium Hyaluronate, Palmitic Acid, Stearic Acid, Tocopherol, Ascorbyl Palmitate, Sodium Phytate, Hydrolyzed Hyaluronic Acid.

*Ingredients from organic farming. 99% natural origin of total. 42% organic of total. COSMOS Organic certified by EcoCert.

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The 72-Hour+ Cream

Formulated for post-procedure skin

What testers reported

89% said post-procedure skin felt soothed on the very first night
84% saw calmer, more comfortable-looking skin within 72 hours
91% would reach for it again after their next treatment

Based on a self-perception survey of 108 testers using The 72-Hour+ Cream nightly for at least 3 nights following an in-clinic aesthetic procedure. Results are self-reported and individual results vary.

What our customers are saying

4.9 average · 100+ verified reviews
Hannah V.

“My provider gave me a sample tube to use right after my session and I immediately ordered the full 50ml size. RF microneedling leaves my face feeling like a fiery sunburn, but putting this on before bed completely took the sting out. Calmed the grid marks and tightness way faster than my usual post-care balm.”

Hannah V.
Hannah V. Verified customer
Taylor

“If you get VI peels or TCA medium peels, you know that 48-hour mark where your skin is tight, itching, and peeling in sheets. Most moisturizers burn like crazy at that stage. This stuff? Pure relief. The aloe + red algae combo is SO cooling. Sinks in fast, doesn't leave that thick greasy vaseline layer on your pillow, and my barrier recovered in record time. Will never do another peel without this stocked.”

Taylor
Taylor Verified customer
Chloe

“I accidentally fried my face combining my tretinoin with a new AHA mask (bad idea). my cheeks were bright red and inflamed. bought this after reading the ingredients had no fragrance or acids. used it for 3 nights in a row and the red patches are completely gone!! face feels normal again instead of dry paper. super gentle”

Chloe
Chloe Verified customer
Claire M.

“Had fractional laser done on my face and neck last Thursday and my skin was feeling right hot and bothered. Was dead nervous about putting anything on it, but this cream is absolutely spot on. Sinks right in without feeling heavy or clogging my pores, and woke up the next morning with the red heat completely gone down. Well chuffed with this purchase.”

Claire M.
Claire M. Verified customer
Danielle K.

“As someone who gets quarterly IPL and clear+brilliant laser treatments, I look for three non-negotiables in post-procedure care: zero fragrance/essential oils, high concentration of calming agents, and multi-depth hydration. Having organic Aloe Vera as the #1 ingredient alongside red algae and dual-weight hyaluronic acid makes this ideal for decreasing TEWL without occluding compromised skin. Absorbs cleanly and supports rapid re-epithelialization.”

Danielle K.
Danielle K. Verified customer
Patricia S.

“I am in my late 50s and get light resurfacing and filler treatments every few months. Many rich post-care creams tend to cause tiny white breakouts or clog my skin, but this formula is different. It feels very comforting, absorbs nicely, and keeps my skin feeling plump and hydrated throughout the critical first three days of healing.”

Patricia S.
Patricia S. Verified customer
Sarah B.

“10/10. I use it after monthly dermaplaning and enzyme peels. It calms down the immediate flushing overnight and leaves my face feeling soft as silk by morning.”

Sarah B.
Sarah B. Verified customer
Loretta P.

“My face was red as a tomato after my SkinPen appointment on Tuesday. I put a good pearl-sized amount of this cream on before bed like my gal suggested, and by Wednesday morning the fire was completely out! It’s creamy, doesn't smell like fake perfume, and feels like a cool drink of water for your skin.”

Loretta P.
Loretta P. Verified customer
Megan K.

“My skin gets extremely reactive whenever I do any clinical treatments - even basic extractions or microdermabrasion leave me red for days. I bought this specifically for the "first 72 hours" window, but honestly, it worked so well at keeping my skin calm that I’ve kept using it as my main nightly moisturizer. Leaves zero greasy residue on my skin and layer seamlessly over my recovery serums.”

Megan K.
Megan K. Verified customer
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The First 72 Hours

When your skin is most vulnerable - and most receptive

Right after microneedling, laser, or a peel, skin is at its most reactive - and what you apply matters most. This post procedure face cream is built for exactly those first three nights: calming the look of redness, easing the feel of tightness, and helping skin look comfortable again by morning.

Visible Benefits
Calms the look of post-procedure redness
Aloe Vera
Supports a comfortable barrier
Red Algae
Eases the feel of tightness
Overnight hydration
Wake up to calmer-looking skin
Nightly use
99% natural origin
COSMOS Organic
Skintelligence

Built for the 72-hour window

Aesthetic procedures work by triggering renewal - and the first 72 hours decide how comfortable that renewal looks and feels. This is recovery skincare in the strictest sense: a calming face cream that leaves out everything aestheticians tell you to avoid, and concentrates on what freshly treated skin actually accepts.

Soothe

Organic aloe vera - the #1 ingredient by concentration - calms the look of redness and delivers water-light hydration reactive skin accepts.

Comfort

Red algae polysaccharides (Hydrolyzed Rhodophyceae) support the feel of a comfortable, protected barrier through the most sensitive recovery hours.

Hydrate

Two molecular weights of hyaluronic acid hold moisture at the surface and below it, so skin looks plumper and feels softer by morning.

Certified Aftercare

Certified organic. Formulated like aftercare.

Most night creams are comfort products with marketing attached. This one is closer to aftercare: a natural face cream where every ingredient is chosen for what freshly treated skin tolerates, audited to the COSMOS Organic standard and certified by EcoCert - organic farming, verified natural origin, and zero synthetic fragrance.

That’s why aestheticians’ usual post-procedure warnings - no retinol, no acids, no essential oils, no fragrance - are simply our ingredient list working as intended.

COSMOS Organic by EcoCert99% natural origin42% organic of totalVegan and fragrance-free
COSMOS Organic certified post-procedure recovery cream - aftercare cream for microneedling laser and peels
Key Ingredients

What’s inside - and why

Organic aloe vera in post-procedure cream for skin after microneedling
Organic Aloe Vera
Soothe
The #1 ingredient by concentration. One of the most clinically respected calming botanicals in skincare - hydrating, cooling-feeling, and gentle enough for the first night after treatment.
Red algae extract in cream after chemical peel and laser aftercare
Red Algae
Comfort
Hydrolyzed Rhodophyceae extract - marine polysaccharides that support the feel of a comfortable, protected barrier during the most sensitive recovery hours.
Jojoba and mango seed butter in fragrance-free post procedure face cream
Jojoba + Mango Butter
Replenish
Organic-farmed lipids that mirror what stressed skin loses - a breathable, non-greasy veil that seals hydration in overnight without clogging.
Dual-weight hyaluronic acid in the best moisturizer after microneedling
Dual-Weight Hyaluronic Acid
Hydrate
Sodium hyaluronate plus hydrolyzed hyaluronic acid - a face cream with hyaluronic acid working at two depths: immediate surface hydration and a lasting-looking plumpness that carries through to morning.
Trusted by Experts

“The first 72 hours after a procedure decide how comfortable your recovery looks. A recovery cream with no retinol, acids, or fragrance - just calming, certified-organic support - is what I want on freshly treated skin. It’s how you protect the treatment you’ve invested in from night one.”

Rachel Donovan, Head of Dermatology at Exosthetics
Rachel Donovan
Head of Dermatology
Expert Reviewed
Questions

Post-procedure care, answered

What should I put on my skin after microneedling?

For the first 72 hours, aestheticians consistently recommend the same thing: nothing active. No retinol, no AHAs or BHAs, no vitamin C, no fragrance - just gentle hydration and barrier-supportive care. That’s exactly the brief this cream is built to: organic aloe, red algae, and hyaluronic acid, with every common irritant left out. Always follow your provider’s aftercare protocol first - it takes priority over any product page, including ours.

When can I start using it after a procedure?

Most providers clear gentle topicals somewhere between the same evening and 72 hours after treatment, depending on the procedure depth. Once yours gives the go-ahead, apply nightly for the first three nights, then keep using it as your evening cream through the rest of recovery. From day 4 onward, many customers transition to Ceramide Repair Complex for longer-term barrier care.

Is this the best moisturizer after microneedling or laser?

Judge any post-procedure cream on four things: no actives that fight healing skin (retinol, acids, essential oils), calming ingredients with real track records, verified formulation standards, and honest labeling. This one is COSMOS Organic certified by EcoCert, 99% natural origin, fragrance-free, and built around aloe + algae - the combination aftercare protocols have trusted for years. If you’re comparing the best night creams for post procedure skin recovery, start by filtering for fragrance-free post-procedure creams - fragrance is the most common irritant on freshly treated skin, which is why this formula contains none. And because the best moisturizer after microneedling for you also depends on your skin, every jar carries a 30-day money-back guarantee.

How is it different from a regular night cream?

Regular night creams optimize for actives - retinol, acids, peptides - because that’s what sells overnight results. Post-procedure skin needs the opposite: a cream that stays out of the way while skin renews. This formula excludes every ingredient aestheticians warn against after treatments and concentrates on comfort, hydration, and the look of calm skin. It’s aftercare in a jar, not an actives vehicle - and between treatments it doubles as a gentle night face cream for sensitive skin.

Does it work as a post laser treatment cream?

Yes - that’s one of its core uses. As a post laser treatment cream it’s applied nightly once your provider clears topicals: typically the same evening for gentle resurfacing, and within 24-72 hours for deeper settings. Customers also reach for it as their moisturizer after Clear and Brilliant, IPL, and fractional sessions, because laser treatment recovery follows the same rule as microneedling - no actives, no fragrance, just calm hydration.

Can I use it during plastic surgery recovery?

On intact, fully closed skin - and only on your surgeon’s timeline. Most people researching the best facial creams for plastic surgery post-procedure care are really after the same shortlist as laser or microneedling patients: fragrance-free, no retinol or acids, certified ingredient standards. This cream fits that brief, but plastic surgery recovery varies by procedure, so your surgeon’s aftercare instructions always come first.

Is this a medicated moisturiser or a facial healing cream?

No - and that distinction matters. The 72-Hour+ Cream is a cosmetic, not a medicated moisturiser or a drug: it does not treat, heal, or prevent any condition. What it does is support the look and feel of calm, comfortable, hydrated skin while your skin does its own work - which is usually what people actually want when they search for a facial healing cream or a post procedure repair cream. If your provider prescribed a medicated product, use it exactly as directed and ask them when a cosmetic cream can join the routine.

What does a complete post procedure skin care routine look like?

Keep it to four steps. A gentle, non-foaming cleanser. A calming post procedure serum - 2-3 drops of our Exosome Serum on clean skin. The 72-Hour+ Cream sealed over it at night. And strict sun protection every morning: mineral SPF is the post procedure sunscreen most providers recommend, and our Daily Defense Moisturiser layers under it. Fewer, better post procedure skin care products beat a crowded shelf - and any 3 Exosthetics products save 15% automatically at checkout.

How do I choose between the best skincare brands for post-procedure care?

Ignore the marketing and audit four things: third-party certification (this cream is COSMOS Organic certified by EcoCert), a fully published ingredient list, zero actives or fragrance, and alignment with what your provider recommends - the same filter medical spas apply when stocking their shelves. The best skincare brands for pre-procedure care pass the same test, just earlier: a week or two of simple, barrier-supportive hydration before treatment helps skin arrive calm, so this routine can start before your appointment, not just after it.

How long does one jar last?

A 50 ml jar used nightly with a pearl-sized amount lasts roughly 6-8 weeks - comfortably covering a procedure recovery cycle plus everyday evening use in between treatments.